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Tamoxifen Tablet is an anti-estrogen that prevents the effects of estrogens on tissues. The precise mechanism of Tamoxifen Tablet’s action is unknown, but one possibility is that it binds and blocks estrogen receptors on the surface of cells, preventing estrogens from binding and activating the cell. Tamoxifen Tablet is used in patients for treating and preventing breast cancer. Tamoxifen Tablets were approved by the FDA in December 1997.
Tamoxifen Tablet is used for the treatment of invasive breast cancer in men and women, the most common type of breast cancer, following surgery and/or radiation and for preventing invasive breast cancer in women at high risk for developing it. Tamoxifen is also used for the treatment of women following surgery and radiation for a less common type of breast cancer called ductal carcinoma in situ (DCIS or intraductal carcinoma). Women who have had DCIS are at high risk for developing invasive breast cancer at a later date, and tamoxifen prevents development of the invasive cancer in almost half of the women during the first five years of treatment. Occasionally, tamoxifen is used to stimulate ovulation.